Norethisterone Enanthate

Written by The Lowdown

|

Medically reviewed by Dr Fran Yarlett

on Nov 8, 2024

Norethisterone enanthate flies solo; a synthetic progestin, it’s used on its own in the contraceptive injection called Noristerat. It’s androgenic and suppresses testosterone in men, which has made it a candidate for a potential hormonal male contraceptive1. Hallelujah.

Once injected into the body, nortethisterone enanthate is quickly converted into norethisterone, and works in the same way with similar side effects.

How does it work?

Norethisterone enanthate is converted into norethisterone. It mainly works by preventing ovulation. It also works by thickening the cervical fluid, which can stop sperm from entering your uterus, and can thin the lining of your uterus in a way that makes it harder for a fertilised egg to implant.

What’s it in?

The Injection

Is it androgenic?

Yes. (Check out our ‘Androgens’ blog for more info on what this means).

What are the side effects?

The following side effects have been recorded for norethisterone when taken by injection3.

  • Menstrual cycle irregularities
  • Acne
  • Headaches
  • Mood changes
  • Nausea
  • Skin reactions
  • Weight changes
  • Bloating4
  • Tender breasts4

References

Social Logo Lowdown

The Lowdown

We are a real-word evidence platform for women’s health that’s visited by almost 2 million women every year. We enable women to review and research their health conditions, symptoms and medications so they can make more informed decisions. Our approach is unique; we provide credible, scientific information alongside reviews from our community of women. We believe that listening to women’s experiences of healthcare is crucial to improving it. Any articles written by "The Lowdown" are written by a range of Lowdown team members and medical professionals.

Our medical review process

This article has been medically reviewed for factual and up to date information by a Lowdown doctor.